Good healthcare needs good evidence from good trials

The Good Clinical Trials Collaborative is a global community initiative that has developed new guidance to promote and enable good randomized controlled trials.

Good randomized controlled trials (RCTs) provide reliable evidence that enables informed changes in healthcare practice. It must be made easier to do good RCTs to inform future care.

Our Guidance was developed in collaboration with a diverse, multidisciplinary group of individuals and organizations with a shared commitment to accelerate better healthcare across the world. Grounded by key scientific and ethical principles, our Guidance provides universally relevant, flexible and quality-focused advice for all parties involved with RCTs.

News 28 September 2022
Good guidance for good trials
Good guidance for good trials Professor Sir Martin Landray
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Good trials are

Good trials are

01 · Informative and relevant

Principle 1 describes the component design characteristics of a RCT that combine to resolve important uncertainties about the effects of a health intervention.

02 · Respectful of participants

Principle 2 outlines key considerations and expectations that support a trial to fulfil its ethical responsibilities regarding participants, future and current patients, and the public.

03 · Collaborative and transparent

Principle 3 addresses the practices and behaviors that help develop trust between all those involved in a trial and contribute to generalized confidence in the clinical trials ecosystem.

04 · Appropriate for their context

Principle 4 outlines the scientific, ethical and efficiency benefits of ensuring that a trial is fit-for-purpose, accounts for and utilizes the inherent characteristics of the trial's setting.

05 · Efficient and well managed

Principle 5 discusses the importance of competent decision-making and coordinated execution, and how good governance and good trial quality management can help achieve these features.

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